⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250878 | 0.82 | — | — | |
| SCHEMBL3082779 | 0.82 | — | — | |
| SCHEMBL251956 | 0.80 | — | — | |
| SCHEMBL251330 | 0.73 | — | — | |
| SCHEMBL5626548 | 0.71 | THRB (0.35) | — | |
| SCHEMBL29700985 | 0.71 | THRB (0.35) | — | |
| SCHEMBL8461054 | 0.68 | THRB (0.30) | — | |
| SCHEMBL981009 | 0.67 | THRB (0.34) | — | |
| Ethylene Glycol SCHEMBL9305497 | 0.66 | — | — | |
| SCHEMBL15352156 | 0.65 | THRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943200-B1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-7994372-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090186998-A1 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE | SPECIALTY COATING SYSTEMS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-7462750-B2 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| US-20070099019-A1 | Parylene variants and methods of synthesis and use | SPECIALTY COATING SYSTEMS, INC. (US) | 2007-05-03 | — | — | US | disclosed |