⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072199 | 0.81 | — | — | |
| SCHEMBL8032768 | 0.75 | — | — | |
| SCHEMBL2123999 | 0.73 | — | — | |
| SCHEMBL13879325 | 0.73 | — | — | |
| SCHEMBL19270306 | 0.71 | — | — | |
| SCHEMBL21872964 | 0.69 | FKBP5 (0.43) | — | |
| SCHEMBL8553313 | 0.68 | — | — | |
| SCHEMBL361260 | 0.65 | CRBN (0.30) | — | |
| SCHEMBL14465775 | 0.60 | — | — | |
| SCHEMBL13812990 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634443-A | Aromatic dihydropyrrole [2,3] cyclobutane compound and synthesis method thereof | 湖南科技学院 | 2022-06-17 | — | — | CN | disclosed |
| US-11312668-B2 | Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose | ABBVIE INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20210017100-A1 | ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE | AbbVie Deutschland GmbH & Co. KG (DE) | 2021-01-21 | — | — | US | disclosed |