Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908416 | 0.88 | DPP4 (0.40) | ACACBDPP4GPR119NAMPTGPR183 | |
| SCHEMBL21344641 | 0.83 | ACACB (0.42) | ACACBGPR119NAMPTKDM4EMAPT | |
| SCHEMBL29392238 | 0.83 | USP30 (0.38) | ACACBDPP4GPR119NAMPTGPR183 | |
| SCHEMBL22908417 | 0.82 | DPP4 (0.35) | ACACBDPP4GPR119NAMPTGPR183 | |
| SCHEMBL21285092 | 0.81 | GPR119 (0.42) | ACACBGPR119NAMPTGPR183KDM4E | |
| SCHEMBL21273942 | 0.78 | GPR183 (0.41) | ACACBGPR119NAMPTGPR183KDM4E | |
| SCHEMBL22908399 | 0.78 | PIK3CA (0.41) | GPR119GPR183 | |
| SCHEMBL29389236 | 0.78 | PIK3CA (0.41) | GPR119GPR183 | |
| Hexane SCHEMBL22345615 | 0.77 | GPR119 (0.38) | ACACBGPR119NAMPTGPR183 | |
| SCHEMBL21361282 | 0.77 | HDAC2 (0.53) | ACACBGPR119HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |