Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 13/20 | 0.66 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.66 |
| ▸ | FLT3 | P36888 | 8/20 | 0.62 |
| ▸ | AURKA | O14965 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | CDK7 | P50613 | 3/20 | 0.51 |
| ▸ | CDK9 | P50750 | 3/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288624 | 0.85 | MEN1 (0.67) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2286993 | 0.84 | MKNK2 (0.85) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2289365 | 0.84 | MKNK2 (0.64) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2284183 | 0.83 | MKNK2 (0.63) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2285515 | 0.81 | CDK2 (0.55) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2281570 | 0.79 | MKNK2 (0.55) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL4158859 | 0.78 | MKNK2 (0.61) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2287258 | 0.76 | MKNK2 (0.55) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL2286099 | 0.76 | MKNK2 (0.52) | MKNK2MKNK1FLT3AURKACDK1 | |
| SCHEMBL4170533 | 0.75 | MKNK2 (0.64) | MKNK2MKNK1FLT3AURKACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | MKNK2 4101/4885MKNK1 4404/4885FLT3 216/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | MKNK2 4185/4885MKNK1 4474/4885FLT3 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.