Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696277 | 0.89 | DRD3 (0.40) | CCR2KCNH2DRD3PDK1 | |
| SCHEMBL23696421 | 0.89 | DRD3 (0.40) | CCR2KCNH2DRD3PDK1 | |
| SCHEMBL22856498 | 0.87 | CCR2 (0.41) | CCR2KCNH2HRH3DRD3PDK1 | |
| SCHEMBL26280371 | 0.87 | CCR2 (0.41) | CCR2KCNH2HRH3DRD3PDK1 | |
| SCHEMBL22906411 | 0.83 | CACNA1H (0.37) | CCR2KCNH2 | |
| SCHEMBL23696566 | 0.83 | BCHE (0.32) | CCR2KCNH2ALDH1A1 | |
| SCHEMBL23695786 | 0.83 | BCHE (0.32) | CCR2KCNH2ALDH1A1 | |
| SCHEMBL24511268 | 0.83 | CACNA1H (0.37) | CCR2KCNH2 | |
| SCHEMBL22793901 | 0.83 | CCR2 (0.39) | CCR2KCNH2HRH3DRD3PDK1 | |
| SCHEMBL23806641 | 0.83 | CCR2 (0.39) | CCR2KCNH2HRH3DRD3PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011871-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |