⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729072 | 0.78 | CA1 (0.33) | — | |
| SCHEMBL22909481 | 0.78 | CA1 (0.33) | — | |
| SCHEMBL29671218 | 0.77 | HDAC6 (0.34) | — | |
| SCHEMBL22909478 | 0.77 | HDAC6 (0.34) | — | |
| SCHEMBL22909271 | 0.74 | CA1 (0.43) | — | |
| SCHEMBL29671194 | 0.74 | F2 (0.32) | — | |
| SCHEMBL22909286 | 0.74 | F2 (0.32) | — | |
| SCHEMBL151989 | 0.70 | — | — | |
| SCHEMBL22909466 | 0.69 | HDAC11 (0.39) | — | |
| SCHEMBL29671207 | 0.68 | CA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559454-B2 | Benzenesulfonamide derivatives and uses thereof | 2692372 ONTARIO, INC. (CA) | 2026-02-24 | — | — | US | disclosed |
| US-20220281812-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC (CA) | 2022-09-08 | — | — | US | disclosed |
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |