Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671218 | 1.00 | HDAC6 (0.34) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL29729072 | 0.82 | CA1 (0.33) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL22909481 | 0.82 | CA1 (0.33) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL22909271 | 0.79 | CA1 (0.43) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL22909286 | 0.78 | F2 (0.32) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL29671194 | 0.78 | F2 (0.32) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL22909153 | 0.77 | — | — | |
| SCHEMBL29671206 | 0.74 | CA1 (0.37) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL22909567 | 0.74 | CA1 (0.37) | HDAC6HDAC3HDAC11HDAC8CA1 | |
| SCHEMBL22909466 | 0.73 | HDAC11 (0.39) | HDAC6HDAC3HDAC11HDAC8CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |