Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671241 | 1.00 | CA12 (0.60) | CA12CA1CA2CA9CA7 | |
| SCHEMBL28762097 | 0.95 | CA12 (0.56) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22909178 | 0.81 | LMNA (0.48) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL29671301 | 0.81 | LMNA (0.48) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| Batabulin SCHEMBL18845 | 0.80 | LMNA (0.54) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| Batabulin SCHEMBL29373304 | 0.80 | LMNA (0.54) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22909398 | 0.79 | LMNA (0.46) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL29671330 | 0.79 | LMNA (0.46) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| Batabulin SCHEMBL6089508 | 0.79 | LMNA (0.53) | CA1CA2ALDH1A1MAPTSMN1; SMN2 | |
| Batabulin SCHEMBL6086887 | 0.79 | LMNA (0.53) | CA1CA2ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |