Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671251 | 1.00 | LMNA (0.49) | LMNAHTTALDH1A1MEN1KMT2A | |
| Batabulin SCHEMBL18845 | 0.90 | LMNA (0.54) | LMNAHTTALDH1A1MEN1KMT2A | |
| Batabulin SCHEMBL29373304 | 0.90 | LMNA (0.54) | LMNAHTTALDH1A1MEN1KMT2A | |
| Batabulin SCHEMBL6089508 | 0.89 | LMNA (0.53) | LMNAHTTALDH1A1MEN1KMT2A | |
| Batabulin SCHEMBL6086887 | 0.89 | LMNA (0.53) | LMNAHTTALDH1A1MEN1KMT2A | |
| Batabulin SCHEMBL7103854 | 0.88 | LMNA (0.48) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL29671221 | 0.86 | LMNA (0.51) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL22909526 | 0.86 | LMNA (0.51) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL22909294 | 0.85 | LMNA (0.50) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL29729041 | 0.85 | LMNA (0.50) | LMNAHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |