Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671271 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTHSD17B10KMT2A | |
| SCHEMBL22909373 | 0.81 | AR (0.45) | SMN1; SMN2KMT2AGAAMEN1 | |
| SCHEMBL22909262 | 0.79 | HDAC6 (0.39) | SMN1; SMN2MAPTHSD17B10MAOB | |
| SCHEMBL29729050 | 0.79 | HDAC6 (0.39) | SMN1; SMN2MAPTHSD17B10MAOB | |
| SCHEMBL29671321 | 0.76 | NPC1 (0.47) | SMN1; SMN2KDM4EMAPTHSD17B10KMT2A | |
| SCHEMBL22909154 | 0.76 | NPC1 (0.47) | SMN1; SMN2KDM4EMAPTHSD17B10KMT2A | |
| SCHEMBL29671295 | 0.73 | ALOX5AP (0.41) | KMT2AMEN1PARP10MAOB | |
| SCHEMBL28762073 | 0.73 | SYK (0.48) | SMN1; SMN2KDM4EMAPTHSD17B10KMT2A | |
| SCHEMBL22909160 | 0.73 | MAPT (0.36) | MAPTGAAALDH1A1 | |
| SCHEMBL29729048 | 0.73 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |