Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729050 | 1.00 | HDAC6 (0.39) | HDAC6ALOX5APFEN1NAMPTMAOB | |
| SCHEMBL22909373 | 0.86 | AR (0.45) | HDAC6SMN1; SMN2CA1CA2LMNA | |
| SCHEMBL22909451 | 0.81 | TSHR (0.48) | ALOX5APFEN1MAOBNPC1RAB9A | |
| SCHEMBL22909344 | 0.80 | PARP10 (0.48) | HDAC6ALOX5APFEN1MAOB | |
| SCHEMBL29671227 | 0.80 | CYP19A1 (0.50) | MAOBCA1CA2 | |
| SCHEMBL29671271 | 0.79 | SMN1; SMN2 (0.43) | MAOBHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL22909370 | 0.79 | SMN1; SMN2 (0.43) | MAOBHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL29729048 | 0.75 | CA1 (0.31) | HDAC6CA1CA2 | |
| SCHEMBL22909160 | 0.75 | MAPT (0.36) | HDAC6PKMCA1CA2MAPT | |
| SCHEMBL22909579 | 0.74 | MAOB (0.43) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |