Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909466 | 0.82 | HDAC11 (0.39) | TSHRHDAC11HDAC8HDAC6LMNA | |
| SCHEMBL22909373 | 0.79 | AR (0.45) | ARHDAC11HDAC8HDAC6LMNA | |
| SCHEMBL22909286 | 0.76 | F2 (0.32) | HDAC11HDAC8HDAC6CA1CA2 | |
| SCHEMBL29671194 | 0.76 | F2 (0.32) | HDAC11HDAC8HDAC6CA1CA2 | |
| SCHEMBL29671257 | 0.75 | CA1 (0.50) | TSHRHDAC11HDAC8HDAC6LMNA | |
| SCHEMBL22909578 | 0.70 | CA2 (0.61) | TSHRHDAC11HDAC8HDAC6LMNA | |
| SCHEMBL22909165 | 0.70 | CA12 (0.61) | TSHRHDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL28434133 | 0.70 | HSP90AA1 (0.43) | HDAC11HDAC8HDAC6LMNAALDH1A1 | |
| SCHEMBL22909481 | 0.70 | CA1 (0.33) | HDAC11HDAC8HDAC6CA1CA2 | |
| SCHEMBL29729072 | 0.70 | CA1 (0.33) | HDAC11HDAC8HDAC6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017843-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 Ontario, Inc. (CA) | 2022-06-29 | — | — | EP | disclosed |
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |