Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729043 | 1.00 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL28762142 | 0.94 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL22909402 | 0.91 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29671193 | 0.91 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL22909171 | 0.87 | SMN1; SMN2 (0.46) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL22909487 | 0.87 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29671298 | 0.87 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29729041 | 0.86 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL22909294 | 0.86 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL22909524 | 0.85 | LMNA (0.44) | LMNAMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |