SCHEMBL2291004

SCHEMBL2291004

CCCCCC(C)C(=O)Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CNR2 P34972 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.46
FAAH O00519 7/20 0.45
CA1 P00915 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ELANE P08246 1/20 0.44
CYP3A4 P08684 2/20 0.43
CA2 P00918 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294692 0.98 PRSS1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL2294967 0.98 PRSS1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL29266799 0.98 PRSS1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL1900961 0.98 PRSS1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL11699133 0.98 PRSS1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL27994629 0.98 PRSS1 (0.50) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL1537155 0.95 CA2 (0.48) PRSS1PRSS2PRSS3ALDH1A1CNR2
SCHEMBL17138201 0.89 PRSS1 (0.43) PRSS1PRSS2PRSS3ALDH1A1CA1
SCHEMBL1794534 0.88 KDM4E (0.48) ALDH1A1TDP1ATML3MBTL1ELANE
SCHEMBL17055505 0.88 KDM4E (0.48) ALDH1A1TDP1ATML3MBTL1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP claimed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US claimed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO claimed
US-11779561-B2 Compounds and pharmaceutical uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-10-10 US disclosed
US-11732223-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc (US) 2023-08-22 US disclosed
US-20220152069-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-05-19 US disclosed
CN-114163437-A Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors 阿雷生物药品公司 2022-03-11 CN disclosed
CN-110382494-B Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors 阿雷生物药品公司 2021-11-16 CN disclosed
US-11001789-B2 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof Crude Spill Cleaning Co. Inc. (US) 2021-05-11 US disclosed
US-20180037850-A1 Solvent compositions for removing petroleum residue from a substrate and methods of use thereof CRUDE SPILL CLEANING COMPANY, INC. 2018-02-08 US disclosed
US-9751880-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and imide compound CANON KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
US-7465395-B2 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY (US) 2008-12-16 US disclosed
EP-1723224-A4 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF TROXLER ELECTRONICS LAB INC (US) 2008-02-27 EP disclosed
US-20070095753-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents CARBONELL RUBEN G 2007-05-03 US disclosed
EP-1723224-A2 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF Troxler Electronics Laboratories, Inc. (US) 2006-11-22 EP disclosed
WO-2005091771-A2 SOLVENT COMPOSITIONS FOR REMOVING PETROLEUM RESIDUE FROM A SUBSTRATE AND METHODS OF USE THEREOF TROXLER ELECTRONICS LABORATORIES, INC. (US) 2005-10-06 WO disclosed
US-20050197267-A1 10-60% by weight aromatic ester, 30-60% by weight aliphatic ester, 0-15% by weight co-solvent, 0-10% by weight cyclic terpene or terpenoid, 0-1% by weight odor-masking agent and 0-20% by weight nonionic surfactant; for removing petroleum residues (e.g., asphalt) from work surface such as truck bed TROXLER ELECTRONICS LABORATORIES, INC. (US) 2005-09-08 US disclosed
EP-1490469-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS North Carolina State University (US) 2004-12-29 EP disclosed
US-20030213747-A1 Methods and compositions for removing residues and substances from substrates using environmentally friendly solvents NORTH CAROLINA STATE UNIVERSITY 2003-11-20 US disclosed
WO-2003072215-A2 METHODS AND COMPOSITIONS FOR REMOVING RESIDUES AND SUBSTANCES FROM SUBSTRATES USING ENVIRONMENTALLY FRIENDLY SOLVENTS NORTH CAROLINA STATE UNIVERSITY (US) 2003-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220152069-A1 COMPOUNDS AND PHARMACEUTICAL USES THEREOF ACE, ACE2, FURIN PRSS1 33/4885PRSS2 17/4885PRSS3 30/4885
US-11779561-B2 Compounds and pharmaceutical uses thereof ACE, ACE2, FURIN PRSS1 33/4885PRSS2 17/4885PRSS3 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.