Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942158 | 0.81 | LTA4H (0.66) | LTA4HNR5A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15559300 | 0.81 | NR5A1 (0.66) | LTA4HNR5A1TP53TSHRKDM4E | |
| SCHEMBL10300046 | 0.81 | NR5A1 (0.66) | LTA4HNR5A1TP53TSHRKDM4E | |
| SCHEMBL28328005 | 0.79 | LTA4H (0.68) | LTA4HNR5A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL16426558 | 0.77 | CYP1A2 (0.49) | LTA4HNR5A1TSHRALDH1A1HPGD | |
| SCHEMBL29390021 | 0.76 | NR5A1 (0.59) | LTA4HNR5A1TP53TSHRKDM4E | |
| SCHEMBL28329203 | 0.76 | LTA4H (0.48) | LTA4HNR5A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28942149 | 0.76 | LTA4H (0.66) | LTA4HNR5A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21340772 | 0.75 | LTA4H (0.37) | LTA4HNR5A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL14882077 | 0.75 | NR5A1 (0.44) | LTA4HNR5A1TP53TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210017110-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | Board of Regents of the Nevada System Higher Education, on behalf of the University of Nevada, Reno (US) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017110-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | AHR, PAH, ALKBH3 | LTA4H 2921/4885NR5A1 3000/4885CHRNB2 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.