Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 6/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744310 | 0.83 | PTPN1 (0.55) | PTPN1APPPTPN2AURKAABL1 | |
| SCHEMBL6673320 | 0.83 | AURKA (0.55) | PTPN1APPPTPN2AURKAABL1 | |
| SCHEMBL9057614 | 0.81 | BAZ2B (0.53) | PTPN1PTPN2BAZ2B | |
| SCHEMBL3152503 | 0.80 | CCR1 (0.46) | PTPN1APPPTPN2AURKAABL1 | |
| SCHEMBL14355084 | 0.79 | CYP11B1 (0.45) | PTPN1PTPN2AURKAABL1NTRK1 | |
| SCHEMBL23742279 | 0.78 | PTPN1 (0.50) | PTPN1APPPTPN2AURKAABL1 | |
| SCHEMBL22678028 | 0.76 | CCR1 (0.56) | PTPN1APPPTPN2AURKAABL1 | |
| SCHEMBL19018467 | 0.75 | CCR1 (0.60) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL16285506 | 0.72 | KIF11 (0.45) | PTPN1APPPTPN2KIF11 | |
| SCHEMBL2540113 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3766875-A1 | COMPOUND AND AN ORGANIC SEMICONDUCTING LAYER, AN ORGANIC ELECTRONIC DEVICE, A DISPLAY DEVICE AND A LIGHTING DEVICE COMPRISING THE SAME | Novaled GmbH (DE) | 2021-01-20 | — | — | EP | disclosed |