Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911939 | 0.80 | MEN1 (0.46) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5495835 | 0.80 | MEN1 (0.51) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL22911990 | 0.76 | HRH4 (0.41) | KDM4E | |
| SCHEMBL5412125 | 0.74 | MEN1 (0.60) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5490225 | 0.74 | MEN1 (0.60) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5491482 | 0.74 | MEN1 (0.60) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5403899 | 0.73 | MEN1 (0.62) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5400137 | 0.73 | MEN1 (0.62) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL22911938 | 0.72 | MEN1 (0.57) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL22911882 | 0.72 | MEN1 (0.53) | MEN1KMT2AMAPK1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |