Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SORD | Q00796 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911891 | 0.80 | GRM4 (0.37) | HRH4GRM4HTR2CCHRM4TSHR | |
| SCHEMBL22911968 | 0.76 | MEN1 (0.51) | KDM4E | |
| SCHEMBL22912012 | 0.74 | GRM4 (0.52) | HRH4GRM4HTR2C | |
| SCHEMBL22911907 | 0.72 | GRM4 (0.49) | HRH4GRM4HTR2CCHRM4DYRK1A | |
| SCHEMBL22911893 | 0.71 | GRM4 (0.55) | HRH4GRM4HTR2CCHRM4 | |
| SCHEMBL29003692 | 0.68 | HRH4 (0.73) | HRH4HTR2CKDM4ETSHRALDH1A1 | |
| SCHEMBL30275021 | 0.68 | HRH4 (0.73) | HRH4HTR2CKDM4ETSHRALDH1A1 | |
| SCHEMBL24704570 | 0.68 | GRM4 (0.46) | GRM4 | |
| SCHEMBL22911878 | 0.67 | GRM4 (0.47) | GRM4 | |
| SCHEMBL4766806 | 0.67 | HRH4 (0.71) | HRH4HTR2CKDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |