Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22252510 | 0.76 | DEGS1 (0.44) | NR4A1NR4A2NR4A3DEGS1KDM1A | |
| SCHEMBL10479693 | 0.74 | DEGS1 (0.43) | NR4A1NR4A2NR4A3DEGS1KDM1A | |
| SCHEMBL19141920 | 0.74 | DEGS1 (0.43) | NR4A1NR4A2NR4A3DEGS1KDM1A | |
| SCHEMBL10479698 | 0.74 | DEGS1 (0.43) | NR4A1NR4A2NR4A3DEGS1KDM1A | |
| SCHEMBL11243121 | 0.72 | KDM1A (0.44) | NR4A1NR4A2NR4A3DEGS1KDM1A | |
| SCHEMBL5858034 | 0.72 | NR4A1 (0.51) | NR4A1NR4A2NR4A3DEGS1CES1 | |
| SCHEMBL5858029 | 0.72 | NR4A1 (0.51) | NR4A1NR4A2NR4A3DEGS1CES1 | |
| SCHEMBL20917036 | 0.71 | DEGS1 (0.43) | NR4A1NR4A2NR4A3DEGS1CES1 | |
| SCHEMBL20917231 | 0.71 | DEGS1 (0.43) | NR4A1NR4A2NR4A3DEGS1CES1 | |
| SCHEMBL20917037 | 0.71 | DEGS1 (0.43) | NR4A1NR4A2NR4A3DEGS1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3522715-B1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-20 | — | — | EP | disclosed |