SCHEMBL22912202

SCHEMBL22912202

C[S+]([O-])c1nc(-c2ccc(=O)n(Cc3ccc(N)cc3)c2)cc(C(F)(F)F)n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SDHB P21912 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19805871 0.89 SDHB (0.69) SDHB
SCHEMBL29976309 0.89 SDHB (0.69) SDHB
SCHEMBL19805761 0.88 SDHB (0.58) SDHB
SCHEMBL19805851 0.87 SDHB (0.52) SDHB
SCHEMBL19805888 0.85 SDHB (0.51) SDHB
SCHEMBL19805633 0.85 SDHB (0.51) SDHB
SCHEMBL29976379 0.85 SDHB (0.70) SDHB
SCHEMBL19805655 0.84 SDHB (0.50) SDHB
SCHEMBL19805648 0.84 SDHB (0.50) SDHB
SCHEMBL19805887 0.83 SDHB (0.51) SDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484854-B1 APOPTOSIS INHIBITORS NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) 2021-01-20 — — EP disclosed
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