SCHEMBL22912254

SCHEMBL22912254

C#CCC[S+]([O-])c1nc(-c2ccc(=O)n(Cc3ccc(OC)c(OC)c3)c2)cc(C(F)(F)F)n1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SDHB P21912 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22912223 0.87 SDHB (0.69) SDHB
SCHEMBL29976379 0.87 SDHB (0.70) SDHB
SCHEMBL29975713 0.87 SDHB (0.62) SDHB
SCHEMBL19806070 0.87 SDHB (0.62) SDHB
SCHEMBL19805821 0.86 SDHB (0.65) SDHB
SCHEMBL19805789 0.85 SDHB (0.63) SDHB
SCHEMBL19805809 0.85 SDHB (0.63) SDHB
SCHEMBL19805816 0.84 SDHB (0.62) SDHB
SCHEMBL19805787 0.84 SDHB (0.60) SDHB
SCHEMBL19805884 0.83 SDHB (0.61) SDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484854-B1 APOPTOSIS INHIBITORS NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) 2021-01-20 — — EP disclosed
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