SCHEMBL2291226

SCHEMBL2291226

CC(F)C(F)(F)OC(F)=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9755313 0.79
SCHEMBL6131434 0.79
SCHEMBL9238498 0.76
SCHEMBL13970968 0.75 ALDH1A1 (0.32)
SCHEMBL1461385 0.72 ALDH1A1 (0.32)
SCHEMBL3135774 0.71
SCHEMBL1313893 0.70
SCHEMBL9445010 0.70
SCHEMBL21701045 0.68 ALDH1A1 (0.33)
SCHEMBL1073724 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8728993-B2 Inert wear resistant PTFE-based solid lubricant nanocomposite UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-05-20 US claimed
US-20130172219-A1 Inert Wear Resistant PTFE-Based Solid Lubricant Nanocomposite THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-07-04 US claimed
US-8383561-B2 Inert wear resistant PTFE-based solid lubricant nanocomposite UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-02-26 US claimed
EP-3008127-B1 WEAR RESISTANT COMPOSITIONS WITH LOW PARTICULATE CONTAMINATION AND METHOD OF MAKING THOSE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-05-30 EP disclosed
US-9328238-B2 Wear resistant compositions with low particulate contamination and method of making those compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-05-03 US disclosed
EP-3008127-A2 WEAR RESISTANT COMPOSITIONS WITH LOW PARTICULATE CONTAMINATION AND METHOD OF MAKING THOSE COMPOSITIONS SABIC Global Technologies B.V. (NL) 2016-04-20 EP disclosed
US-9315628-B2 Permanent attachment of agents to surfaces containing C-H functionality UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2016-04-19 US disclosed
US-20140371378-A1 WEAR RESISTANT COMPOSITIONS WITH LOW PARTICULATE CONTAMINATION AND METHOD OF MAKING THOSE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2014-12-18 US disclosed
WO-2014199322-A2 WEAR RESISTANT COMPOSITIONS WITH LOW PARTICULATE CONTAMINATION AND METHOD OF MAKING THOSE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-12-18 WO disclosed
EP-2731999-A2 PERMANENT ATTACHMENT OF AGENTS TO SURFACES CONTAINING C-H FUNCTIONALITY University of Georgia Research Foundation, Inc. (US) 2014-05-21 EP disclosed
US-8728993-B2 Inert wear resistant PTFE-based solid lubricant nanocomposite UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-05-20 US disclosed
US-20110195879-A1 INERT WEAR RESISTANT FLUOROPOLYMER-BASED SOLID LUBRICANTS, METHODS OF MAKING AND METHODS OF USE SAWYER WALLACE GREGORY 2011-08-11 US disclosed
EP-2352792-A2 INERT WEAR RESISTANT FLUOROPOLYMER-BASED SOLID LUBRICANTS, METHODS OF MAKING, AND METHODS OF USE University of Florida Research Foundation, Inc. (US) 2011-08-10 EP disclosed
US-20110054102-A1 Inert Wear Resistant PTFE-Based Solid Lubricant Nanocomposite AIR FORCE, UNITED STATES 2011-03-03 US disclosed
US-7790658-B2 Inert wear resistant PTFE-based solid lubricant nanocomposite University of Florida Research Foundaction, Inc. (US) 2010-09-07 US disclosed
WO-2010057163-A2 INERT WEAR RESISTANT FLUOROPOLYMER-BASED SOLID LUBRICANTS, METHODS OF MAKING, AND METHODS OF USE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2010-05-20 WO disclosed
US-20070105726-A1 Inert wear resistant PTFE-based solid lubricant nanocomposite UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-05-10 US disclosed
WO-2006128128-A2 INERT WEAR RESISTANT PTFE-BASED SOLID LUBRICANT NANOCOMPOSITE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2006-11-30 WO disclosed
US-6540866-B1 Method for lamination of fluoropolymer to metal and printed circuit board (PCB) substrate INSTITUTE OF MICROELECTRONICS (SG) 2003-04-01 US disclosed
US-6334926-B1 Method for low temperature lamination of metals to fluoropolymers NATIONAL UNIVERSITY OF SINGAPORE AND INSTITUTE OF MICROELECTRONICS (SG) 2002-01-01 US disclosed