Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 10/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | FUBP1 | Q96AE4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | UBE2I | P63279 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805724 | 0.89 | SDHB (0.49) | SDHBADORA2AADORA1FUBP1TSHR | |
| SCHEMBL19805725 | 0.79 | SDHB (0.49) | SDHB | |
| SCHEMBL19805712 | 0.77 | SDHB (0.49) | SDHBKMT2A | |
| SCHEMBL19805721 | 0.75 | SDHB (0.68) | SDHB | |
| SCHEMBL26312682 | 0.75 | SDHB (0.54) | SDHBSMN1; SMN2LMNAKMT2A | |
| SCHEMBL19805713 | 0.75 | SDHB (0.51) | SDHBTSHRSMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL19805714 | 0.73 | SDHB (0.49) | SDHBHSD17B10KDM4EALDH1A1 | |
| SCHEMBL20985714 | 0.73 | SDHB (0.54) | SDHB | |
| SCHEMBL20985681 | 0.72 | SDHB (0.54) | SDHBMAPTTP53SMN1; SMN2LMNA | |
| SCHEMBL29976379 | 0.72 | SDHB (0.70) | SDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |