Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | GSR | P00390 | 7/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 3/20 | 0.49 |
| ▸ | HBB | P68871 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20087088 | 0.95 | MBNL1 (0.64) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL20087038 | 0.95 | MBNL1 (0.64) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL20087085 | 0.95 | MBNL1 (0.64) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL18163883 | 0.91 | MBNL1 (0.70) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL18163888 | 0.91 | MBNL1 (0.70) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL18163885 | 0.91 | MBNL1 (0.70) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL18163922 | 0.91 | MBNL1 (0.70) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL18163842 | 0.91 | MBNL1 (0.70) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL20091298 | 0.90 | MBNL1 (0.71) | MBNL1ADORA2AKMT2AMEN1TDP1 | |
| SCHEMBL18163843 | 0.89 | MBNL1 (0.70) | MBNL1ADORA2AKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283463-B1 | DIMERIC QUINACRINE DERIVATIVES AS AUTOPHAGY INHIBITORS FOR CANCER THERAPY | UNIV PENNSYLVANIA (US) | 2021-01-20 | — | — | EP | disclosed |