SCHEMBL22913541

SCHEMBL22913541

Brc1cccc2c1sc1ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.39
ABCG2 Q9UNQ0 5/20 0.39
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
ALOX5 P09917 1/20 0.36
ABCB1 P08183 1/20 0.36
ATM Q13315 1/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
USP2 O75604 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22329253 0.87 ALOX5 (0.46) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL25270552 0.87 LIMK1 (0.47) LIMK1ALDH1A1ALOX5MAPK1PIM1
SCHEMBL22700404 0.86 ALOX5 (0.45) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL22329723 0.86 ALOX5 (0.45) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL22330295 0.86 ALOX5 (0.45) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL22329760 0.85 ALOX5 (0.50) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL22700410 0.85 ALOX5 (0.50) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL22329251 0.84 ALOX5 (0.49) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL17425609 0.84 ALOX5 (0.49) LIMK1ADORA2AADORA1MEN1KMT2A
SCHEMBL23349928 0.84 ALOX5 (0.49) LIMK1ADORA2AADORA1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015497-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-01-28 WO disclosed