Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22914976 | 0.92 | PDK2 (0.46) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL23956300 | 0.92 | PDK2 (0.46) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL19831173 | 0.91 | PDK2 (0.47) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL19500915 | 0.89 | PDK2 (0.47) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL21290007 | 0.88 | FFAR1 (0.43) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL25101002 | 0.88 | FFAR1 (0.43) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL25100964 | 0.88 | FFAR1 (0.43) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL21250874 | 0.86 | GRM5 (0.41) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL19833337 | 0.85 | CCR1 (0.45) | PDK2GRM5LMNASMN1; SMN2MAPT | |
| SCHEMBL14425486 | 0.85 | KDM4E (0.52) | GRM5LMNASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013775-A1 | METHOD FOR PRODUCING ORTHO-METALLATED METAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-01-28 | — | — | WO | disclosed |