Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.36 |
| ▸ | GRPR | P30550 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290007 | 1.00 | FFAR1 (0.43) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL25100964 | 1.00 | FFAR1 (0.43) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL21290404 | 0.94 | FFAR1 (0.43) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL21290071 | 0.94 | FFAR1 (0.43) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL26550027 | 0.93 | FFAR1 (0.44) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL22914977 | 0.88 | PDK2 (0.45) | HRH3PDK2GRM5HIF1AHTT | |
| SCHEMBL21290226 | 0.87 | TGFBR1 (0.43) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL23487554 | 0.86 | FFAR1 (0.45) | FFAR1BRS3HRH3FAAHCES1 | |
| SCHEMBL26549053 | 0.86 | BRS3 (0.41) | FFAR1BRS3PDK2GRM5TSHR | |
| SCHEMBL25100830 | 0.85 | CYP11B1 (0.38) | FFAR1BRS3HRH3FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |