Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GGH | Q92820 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22915234 | 0.85 | AKT1 (0.35) | — | |
| SCHEMBL23189180 | 0.82 | FNTA (0.36) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL8835130 | 0.72 | KDM4E (0.60) | FOLH1GAAKDM4EALDH1A1TP53 | |
| SCHEMBL24042581 | 0.71 | FOLH1 (0.35) | BMP1FOLH1NAALAD2RIMKLA | |
| SCHEMBL24042582 | 0.71 | FOLH1 (0.35) | BMP1FOLH1NAALAD2RIMKLA | |
| SCHEMBL23813145 | 0.71 | FOLH1 (0.35) | BMP1FOLH1NAALAD2RIMKLA | |
| SCHEMBL24042600 | 0.70 | FOLH1 (0.34) | BMP1FOLH1NAALAD2RIMKLA | |
| SCHEMBL17254417 | 0.70 | DNMT1 (0.32) | ALDH1A1HPGDCYP1A2 | |
| SCHEMBL23419842 | 0.68 | BMP1 (0.49) | BMP1FOLH1MMP9MMP8MMP13 | |
| SCHEMBL21413554 | 0.68 | DNMT1 (0.40) | GAAKDM4EALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3769786-A1 | ANTIBODY-DRUG CONJUGATE HAVING ACIDIC SELF-STABILIZATION JUNCTION | Sichuan Baili Pharm Co. Ltd (CN) | 2021-01-27 | — | — | EP | disclosed |