Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22915718 | 0.81 | CDK2 (0.60) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL12522769 | 0.81 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL24649386 | 0.80 | ADORA2A (0.48) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL12522765 | 0.78 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL20857246 | 0.77 | CDK1 (0.49) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL21562148 | 0.77 | CDK1 (0.49) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL14087936 | 0.75 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL15887583 | 0.75 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL129642 | 0.73 | CDK1 (0.68) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL14619498 | 0.72 | CDK2 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013234-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | BEIGENE, LTD. (KY) | 2021-01-28 | — | — | WO | disclosed |