Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287874 | 1.00 | GPR119 (0.50) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL2287878 | 1.00 | GPR119 (0.50) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL13876978 | 0.87 | KDM4E (0.56) | GPR119SLC2A1KDM4EPKMYAP1 | |
| SCHEMBL30876501 | 0.85 | SLC2A1 (0.53) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL30876487 | 0.85 | SLC2A1 (0.53) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL22406147 | 0.85 | SLC2A1 (0.53) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL31298894 | 0.84 | SCN9A (0.49) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL19610292 | 0.84 | GPR119 (0.54) | GPR119SLC2A1CHEK2KDM4EPKM | |
| SCHEMBL2227838 | 0.83 | SLC6A2 (0.52) | KDM4ESLC6A2SLC6A4HTR3AKCNH2 | |
| SCHEMBL2285047 | 0.83 | SLC6A2 (0.52) | KDM4ESLC6A2SLC6A4HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089550-A1 | ALKYL-HETEROCYCLE CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2011-07-28 | — | — | WO | disclosed |