Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 17/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 16/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | SDHB | P21912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852396 | 1.00 | NR1H2 (0.46) | NR1H2NR1H3LOXL2RXRASDHB | |
| SCHEMBL29852265 | 0.90 | LOXL2 (0.41) | NR1H2NR1H3LOXL2 | |
| SCHEMBL22918249 | 0.90 | LOXL2 (0.41) | NR1H2NR1H3LOXL2 | |
| SCHEMBL22918326 | 0.87 | LOXL2 (0.43) | NR1H2LOXL2 | |
| SCHEMBL29852271 | 0.87 | LOXL2 (0.43) | NR1H2LOXL2 | |
| SCHEMBL22918327 | 0.80 | KMT2A (0.40) | LOXL2 | |
| SCHEMBL29852658 | 0.80 | KMT2A (0.40) | LOXL2 | |
| SCHEMBL22918247 | 0.78 | AOC3 (0.39) | LOXL2 | |
| Hydrochloric Acid SCHEMBL28703580 | 0.77 | AOC3 (0.38) | LOXL2 | |
| SCHEMBL22918336 | 0.76 | LOXL2 (0.38) | NR1H2NR1H3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012014-A1 | DIFLUOROHALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES, METHODS OF PREPARATION, AND USES THEREOF | PHARMAXIS LTD. (AU) | 2021-01-28 | — | — | WO | disclosed |