Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.66 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | PTAFR | P25105 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825278 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL17065552 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL2294152 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL30986129 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL673766 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL479274 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL14967280 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL479199 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL479150 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT | |
| SCHEMBL671970 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NR5A2NR5A1RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263531-A1 | METHODS FOR THE TREATMENT AND AMELIORATION OF ATOPIC DERMATITIS | JADO TECHNOLOGIES GMBH | 2011-10-27 | — | — | US | disclosed |
| US-7998945-B2 | Methods for the treatment and amelioration of atopic dermatitis | JADO TECHNOLOGIES GMBH (DE) | 2011-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263531-A1 | METHODS FOR THE TREATMENT AND AMELIORATION OF ATOPIC DERMATITIS | PHOSPHO1, SMPD3, SMPD1 | SMN1; SMN2 4002/4885NR5A2 4616/4885NR5A1 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.