Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.69 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.61 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.61 |
| ▸ | AMD1 | P17707 | 2/20 | 0.55 |
| ▸ | AHCY | P23526 | 3/20 | 0.54 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291893 | 0.88 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL19991769 | 0.87 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL15395684 | 0.84 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9970148 | 0.84 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL17777367 | 0.84 | DOT1L (0.61) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL14174703 | 0.83 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL15395441 | 0.83 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9970622 | 0.83 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL24146588 | 0.82 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL308385 | 0.82 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |