SCHEMBL308385

SCHEMBL308385

CC1(C)O[C@@H]2[C@H](O1)[C@@H](CO)O[C@H]2n1cnc2c(N)ncnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 1.00
PI4K2B Q8TCG2 2/20 1.00
PI4K2A Q9BTU6 2/20 1.00
PI4KB Q9UBF8 2/20 1.00
RXFP1 Q9HBX9 1/20 0.69
GAA P10253 1/20 0.66
OR51E2 Q9H255 1/20 0.66
P2RX1 P51575 1/20 0.65
P2RX3 P56373 1/20 0.65
P2RX4 Q99571 1/20 0.65
ADORA3 P0DMS8 4/20 0.65
ADORA2A P29274 2/20 0.65
DPP4 P27487 1/20 0.65
MEN1 O00255 1/20 0.65
SLC28A1 O00337 1/20 0.65
MAP3K7 O43318 1/20 0.65
SLC28A2 O43868 1/20 0.65
GAPDH P04406 1/20 0.65
MAPK1 P28482 1/20 0.65
ADORA2B P29275 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29803977 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL17568786 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL13901805 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL18125984 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL13986328 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL24146588 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL9970446 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL22393059 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL20483753 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1
SCHEMBL29380625 1.00 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 EP disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
US-20260115216-A1 NUCLEIC ACID PRECURSOR KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2026-04-30 US disclosed
EP-4704854-A2 PRMT INHIBITOR COMPOUNDS AND THE USES THEREOF Purdue Research Foundation (US) 2026-03-11 EP disclosed
US-20260000698-A1 SARS-COV-2 NSP14 METHYLTRANSFERASE INHIBITORS UNIV MINNESOTA (US) 2026-01-01 US disclosed
EP-4045498-B1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS UNIV CALIFORNIA (US) 2025-12-03 EP disclosed
US-20250228855-A1 PYRAZINAMIDE COMPOUNDS MASSACHUSETTS GEN HOSPITAL (US) 2025-07-17 US disclosed
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 US disclosed
US-20250093263-A1 FRET-BASED ASSAYS THE GENERAL HOSPITAL CORPORATION 2025-03-20 US disclosed
WO-2025043152-A1 METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-27 WO disclosed
WO-2004013300-A2 COMPOUNDS WITH THE BICYCLO[4.2.1]NONANE SYSTEM FOR THE TREATMENT OF FLAVIVIRIDAE INFECTIONS PHARMASSET INC. (US) 2004-02-12 WO disclosed
US-6670461-B1 Bi-, tri, or polycyclic nucleoside analogues having a \"locked\" structure capable of forming heat resistant nucleobase specific duplexes and triplexes with single and double stranded nucleic acids. EXIQON A/S (DK) 2003-12-30 US disclosed
US-20030134808-A1 Oligonucleotide analogues WENGEL JESPER (DK) 2003-07-17 US disclosed
US-20020161220-A1 Tetraphosphonate bicyclic trisanhydrides GILEAD PHARMASSET LLC 2002-10-31 US disclosed
US-6326490-B1 ANTIPROLIFERATION AGENTS OR ANTICARCINOGENIC AGENTS PHARMASSET, LTD. 2001-12-04 US disclosed
US-5700786-A Analogues of adenosine 5'diphosphate and pharmaceutical compositions thereof SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1997-12-23 US disclosed
US-5658890-A INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1997-08-19 US disclosed
US-5569650-A C-nucleoside isosters of analogs thereof and pharmaceutical compositions SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-10-29 US disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed
US-4056673-A VIRICIDE, ANTINEOPLASTIC HOFFMANN-LA ROCHE INC. (US) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C PI4KA 2171/4885PI4K2B 2027/4885PI4K2A 2663/4885
US-20030134808-A1 Oligonucleotide analogues TARBP1, DCLRE1B, ADAR PI4KA 3880/4885PI4K2B 4159/4885PI4K2A 3812/4885
US-12630527-B2 Broad spectrum anti-cancer compounds YTHDF3, YTHDF1, YTHDF2 PI4KA 1587/4885PI4K2B 1126/4885PI4K2A 1157/4885
US-20250093263-A1 FRET-BASED ASSAYS TARBP1, GTPBP4, TERF2IP PI4KA 2154/4885PI4K2B 2299/4885PI4K2A 2633/4885
US-20260115216-A1 NUCLEIC ACID PRECURSOR NSUN2, POLRMT, SSU72 PI4KA 1774/4885PI4K2B 1586/4885PI4K2A 1567/4885
US-20250228855-A1 PYRAZINAMIDE COMPOUNDS PC, GOT2, PCK2 PI4KA 543/4885PI4K2B 701/4885PI4K2A 645/4885
US-20260000698-A1 SARS-COV-2 NSP14 METHYLTRANSFERASE INHIBITORS NSUN2, SARS1, RNMT PI4KA 2862/4885PI4K2B 2542/4885PI4K2A 3099/4885
US-20020161220-A1 Tetraphosphonate bicyclic trisanhydrides IDH1, PPIP5K2, DHPS PI4KA 857/4885PI4K2B 1224/4885PI4K2A 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.