Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.71 |
| ▸ | THPO | P40225 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022230 | 0.91 | CYP1A2 (0.67) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL2292121 | 0.87 | RXFP1 (0.57) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL7206725 | 0.86 | PI4KA (0.59) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL10399490 | 0.85 | PI4KA (0.57) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL2294904 | 0.84 | PI4KA (0.66) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL11518212 | 0.84 | PI4KA (0.65) | ADORA2ACYP1A2ADORA2BTHPOPI4KA | |
| SCHEMBL29387702 | 0.83 | CYP1A2 (1.00) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL725689 | 0.83 | CYP1A2 (1.00) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL29753859 | 0.83 | CYP1A2 (1.00) | ADORA2ACYP1A2ADORA2BTHPOMEN1 | |
| SCHEMBL725690 | 0.83 | CYP1A2 (1.00) | ADORA2ACYP1A2ADORA2BTHPOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | ADORA2A 2428/4885CYP1A2 1137/4885ADORA2B 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.