Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.66 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.66 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.66 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.66 |
| ▸ | CD99 | P14209 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288205 | 0.86 | RXFP1 (0.60) | PI4KAPI4K2BPI4K2API4KBCD99 | |
| SCHEMBL2292011 | 0.84 | ADORA2A (0.71) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13314808 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13296260 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL5052443 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL25242659 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL24146589 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL24146587 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL2111246 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL325225 | 0.84 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989430-B2 | Antibacterial agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | PI4KA 4490/4885PI4K2B 3867/4885PI4K2A 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.