Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22642652 | 0.92 | PRKCA (0.47) | PRKCANAAAALOX5DGKA | |
| SCHEMBL18970778 | 0.90 | PRKCA (0.46) | PRKCANAAAALOX5DGKA | |
| SCHEMBL20626657 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL21953750 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL18665275 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL24344812 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL20887283 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL25004569 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL21242959 | 0.83 | MAPT (0.42) | PRKCANAAA | |
| SCHEMBL22430757 | 0.83 | MAPT (0.42) | PRKCANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458590-B9 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3458590-B1 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-01-27 | — | — | EP | disclosed |