Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 8/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19032708 | 0.92 | GNAI3 (0.58) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19040869 | 0.92 | GNAI3 (0.58) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19032438 | 0.88 | GNAI3 (0.50) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL21999942 | 0.88 | GNAI3 (0.47) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL20684331 | 0.86 | GNAI3 (0.52) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL21423430 | 0.86 | GNAI3 (0.48) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL19032509 | 0.86 | GNAI3 (0.48) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL30304096 | 0.81 | GNAI3 (0.53) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL16072733 | 0.79 | GNAI3 (0.68) | GNAI3GNAO1GNAI1BCHEACHE | |
| SCHEMBL16072734 | 0.79 | GNAI3 (0.68) | GNAI3GNAO1GNAI1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458590-B1 | POLYNUCLEOTIDES ENCODING -GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE | MODERNATX INC (US) | 2021-01-27 | — | — | EP | disclosed |