SCHEMBL22920764

SCHEMBL22920764

CC1(C)c2ccccc2-c2c(Cl)cc3[nH]c4ccccc4c3c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 0.40
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
CHEK1 O14757 7/20 0.36
WEE1 P30291 6/20 0.36
CDK2 P24941 3/20 0.36
CAMK2D Q13557 3/20 0.36
CCNE2 O96020 2/20 0.36
CDK4 P11802 2/20 0.36
CCND1 P24385 2/20 0.36
CCNE1 P24864 2/20 0.36
CAMK2B Q13554 2/20 0.36
CAMK2G Q13555 2/20 0.36
CAMK2A Q9UQM7 2/20 0.36
CDK5 Q00535 3/20 0.36
PRKACA P17612 2/20 0.36
GSK3A P49840 2/20 0.36
GSK3B P49841 2/20 0.36
PRKCQ Q04759 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730495 0.77 CHEK1 (0.44) PARP1CHEK1CDK2CAMK2DCCNE2
SCHEMBL17849736 0.77 CDK4 (0.49) PARP1KDM4ELMNACHEK1CDK2
SCHEMBL20160592 0.76 PARP1 (0.43) PARP1KDM4ELMNAHTTCHEK1
SCHEMBL24730498 0.76 PGR (0.40) PARP1KDM4ELMNACHEK1CDK2
SCHEMBL10014085 0.76 PARP1 (0.47) PARP1KDM4ELMNAHTTCHEK1
SCHEMBL29819533 0.76 PARP1 (0.47) PARP1KDM4ELMNAHTTCHEK1
SCHEMBL26380587 0.75 PDK2 (0.38) KDM4ELMNAHTTPDK2MEN1
SCHEMBL15940475 0.74 PARP1 (0.39) PARP1KDM4ELMNAHTTCHEK1
SCHEMBL29506381 0.74 CHEK1 (0.43) PARP1KDM4ELMNACHEK1CDK2
SCHEMBL16310278 0.74 CDK4 (0.49) PARP1KDM4ELMNACHEK1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015555-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-01-28 WO disclosed