SCHEMBL22920952

SCHEMBL22920952

CC1(C)c2ccccc2-c2ccc3c(c21)C(C)(C)c1ccc(Cl)cc1-3

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.53
PGR P06401 2/20 0.46
S100A4 P26447 1/20 0.42
AKR1A1 P14550 1/20 0.41
AKR1B1 P15121 1/20 0.41
GPR3 P46089 1/20 0.37
PPOX P50336 1/20 0.35
PTH1R Q03431 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19849937 0.89 PDK2 (0.59) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL22920723 0.87 PDK2 (0.44) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL20806340 0.86 PDK2 (0.56) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL24969748 0.83 PDK2 (0.50) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL24969167 0.83 PDK2 (0.43) PDK2PGRS100A4
SCHEMBL25818609 0.83 PDK2 (0.39) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL22920934 0.83 PDK2 (0.43) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL1922761 0.82 PDK2 (0.54) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL29402770 0.82 PDK2 (0.54) PDK2PGRS100A4AKR1A1AKR1B1
SCHEMBL21510875 0.82 S100A4 (0.50) PDK2PGRS100A4AKR1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015555-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-01-28 WO disclosed