Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.45 |
| ▸ | F3 | P13726 | 9/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227180 | 0.87 | SELP (0.60) | SELPMEN1POLBKMT2APTPN1 | |
| SCHEMBL2227184 | 0.87 | SELP (0.60) | SELPMEN1POLBKMT2APTPN1 | |
| SCHEMBL18891650 | 0.87 | SELP (0.58) | SELPMEN1POLBKMT2APTPN1 | |
| SCHEMBL19399306 | 0.85 | SELP (0.56) | SELPMEN1POLBKMT2APTPN1 | |
| SCHEMBL19399305 | 0.85 | SELP (0.56) | SELPMEN1POLBKMT2APTPN1 | |
| SCHEMBL18891847 | 0.84 | SELP (0.57) | SELPMEN1POLBKMT2APTPN1 | |
| SCHEMBL19343765 | 0.84 | SELP (0.57) | SELPPTPN1F10F3ATM | |
| SCHEMBL13042681 | 0.84 | F10 (0.62) | SELPPTPN1F10 | |
| SCHEMBL2023746 | 0.84 | F10 (0.62) | SELPPTPN1F10 | |
| SCHEMBL18891551 | 0.84 | SELP (0.55) | SELPMEN1POLBKMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259249-A1 | INHIBITORS OF ANTIBIOTIC RESISTANCE MEDIATED BY ARNT | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2022-08-18 | — | — | US | disclosed |
| WO-2021014422-A1 | INHIBITORS OF ANTIBIOTIC RESISTANCE MEDIATED BY ARN T | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259249-A1 | INHIBITORS OF ANTIBIOTIC RESISTANCE MEDIATED BY ARNT | ARNT, LCAT, GNPAT | SELP 2829/4885MEN1 3768/4885POLB 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.