ARNT — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15740044	1.00	15/20
SCHEMBL15740064	1.00	15/20
SCHEMBL15740052	0.65	15/20
SCHEMBL15717081	1.00	14/20
SCHEMBL15739998	1.00	14/20
SCHEMBL15740003	1.00	14/20
SCHEMBL15740004	1.00	14/20
SCHEMBL15740015	1.00	14/20
SCHEMBL15740089	1.00	14/20
SCHEMBL15740049	0.85	14/20
SCHEMBL18055781	0.81	14/20
SCHEMBL15740055	0.77	14/20
SCHEMBL18055799	0.76	14/20
SCHEMBL15740115	0.76	14/20
SCHEMBL15739995	0.70	14/20
SCHEMBL11014495	0.54	14/20
SCHEMBL15740005	1.00	13/20
SCHEMBL15740037	1.00	13/20
SCHEMBL15740048	1.00	13/20
SCHEMBL18055782	0.76	13/20

Clinical trials — most relevant to ARNT by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients	PHASE4	NOT_YET_RECRUITING
Exogenous Melatonin in Intensive Care Unit Chronodisruption	PHASE3	UNKNOWN
Fibrates in Pediatric Cholestasis	PHASE2	COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
Study of the Effects of Iron on Lung Blood Pressure at High Altitude	PHASE2	WITHDRAWN
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients	PHASE2	COMPLETED
Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer	PHASE1/PHASE2	RECRUITING
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Multiple N-of-1 Trials of (Intermittent) Hypoxia Therapy in Parkinson's Disease	PHASE1/PHASE2	COMPLETED
The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation	nan	COMPLETED
Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders	nan	UNKNOWN
Molecular Epidemiology of Dioxin-Related Illness in Seveso	nan	COMPLETED
Involvement of Pollutants in Atopic Dermatitis and Psoriasis	nan	UNKNOWN
Melatonin Receptor Agonist and Peripheral Biological Markers	nan	COMPLETED
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery	nan	COMPLETED
Epidemiology of Pituitary Tumours: Prevalence of Associated Neoplasia	nan	UNKNOWN
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages	nan	COMPLETED
A Study of the Interaction Between Tumor Susceptibility Gene Glycine N-methyltransferase (GNMT) and Lung Cancer	nan	UNKNOWN
Human Study of Hydroxytyrosol on Phase II Enzymes in Healthy Subjects	nan	COMPLETED
Hypoxia Inducible Factor 1 Alpha as a Novel Biomarker in Septic Shock	nan	COMPLETED
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure	nan	UNKNOWN
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories	nan	RECRUITING
Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients	nan	COMPLETED
Study of the Effects of Iron Levels on the Lungs at High Altitude	nan	COMPLETED
Gut Microbiome Analysis in Organ Transplant Recipient	nan	NOT_YET_RECRUITING
Genes-in-Action - Hepcidin Regulation of Iron Supplementation	nan	COMPLETED
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a ARNT binder may also engage these)

Protein	Name	Similarity
Q9BE97	—	1.000	Q9BE97 →
O02748	—	1.000	O02748 →
P41739	—	1.000	P41739 →
Q9DG12	—	1.000	Q9DG12 →
Q78E60	—	1.000	Q78E60 →
Q61324	—	0.999	Q61324 →
P79832	—	0.999	P79832 →
P53762	—	0.997	P53762 →
Q9HBZ2	—	0.997	Q9HBZ2 →
Q5R4T2	—	0.997	Q5R4T2 →
Q7TN99	—	0.996	Q7TN99 →
Q6YGZ5	—	0.994	Q6YGZ5 →
Q91YA9	—	0.994	Q91YA9 →
Q9EPW1	—	0.994	Q9EPW1 →
AHR	Aryl hydrocarbon receptor	0.994	landscape →
P49844	—	0.993	P49844 →
Q8QGQ8	—	0.993	Q8QGQ8 →
P06537	—	0.993	P06537 →
O00327	—	0.993	O00327 →
A0MLS5	—	0.993	A0MLS5 →
O88529	—	0.993	O88529 →
Q297L2	—	0.992	Q297L2 →
Q8CJE2	—	0.992	Q8CJE2 →
Q84T61	—	0.992	Q84T61 →
Q9WTL8	—	0.992	Q9WTL8 →
Q26263	—	0.992	Q26263 →
Q91904	—	0.992	Q91904 →
A0A0J9UPF5	—	0.992	A0A0J9UPF5 →
C5DX31	—	0.992	C5DX31 →
Q9JHS1	—	0.992	Q9JHS1 →