SCHEMBL22922415

SCHEMBL22922415

CN(CC(O)C1CCOCC1)C(=O)I

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.38
BCL2A1 Q16548 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5065098 0.71 PIK3CD (0.36) PIK3CD
SCHEMBL8948028 0.69 PIK3CD (0.40) PIK3CDBCL2A1
SCHEMBL9965028 0.68 PIK3CD (0.33) PIK3CD
SCHEMBL22858751 0.66 NSD2 (0.38) PIK3CD
SCHEMBL22858752 0.66 NSD2 (0.38) PIK3CD
SCHEMBL25211159 0.65 TP53 (0.34) PIK3CD
SCHEMBL10608216 0.65 TP53 (0.34) PIK3CD
SCHEMBL1774348 0.65 TP53 (0.34) PIK3CD
SCHEMBL19722917 0.65 PIK3CD (0.42) PIK3CD
SCHEMBL5987664 0.64 PIK3CD (0.39) PIK3CDBCL2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021013083-A1 TRICYCLIC COMPOUNDS AS HPK1 INHIBITOR AND THE USE THEREOF BEIGENE, LTD. (KY) 2021-01-28 WO disclosed