Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.30 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442424 | 0.79 | TP53 (0.50) | ALDH1A1TDP1SMN1; SMN2VKORC1 | |
| SCHEMBL6064540 | 0.79 | TP53 (0.50) | ALDH1A1TDP1SMN1; SMN2VKORC1 | |
| SCHEMBL12469225 | 0.77 | TSHR (0.41) | ALDH1A1TDP1 | |
| SCHEMBL12861257 | 0.76 | PIK3CD (0.40) | PIK3CDALDH1A1TDP1BCL2A1 | |
| SCHEMBL9965028 | 0.74 | PIK3CD (0.33) | PIK3CDIDO1 | |
| SCHEMBL17154093 | 0.72 | PIK3CD (0.39) | PIK3CDSMN1; SMN2BCL2A1 | |
| SCHEMBL25211159 | 0.72 | TP53 (0.34) | PIK3CDIDO1SMN1; SMN2 | |
| SCHEMBL1774348 | 0.72 | TP53 (0.34) | PIK3CDIDO1SMN1; SMN2 | |
| SCHEMBL10608216 | 0.72 | TP53 (0.34) | PIK3CDIDO1SMN1; SMN2 | |
| SCHEMBL24298770 | 0.70 | TP53 (0.60) | IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484949-A | Method for the synthesis of α β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0454867-B1 | A METHOD FOR THE SYNTHESIS OF $g(a), $g(b)-UNSATURATED KETONES | NIPPON SODA CO (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0454867-A1 | A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. | NIPPON SODA CO (JP) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991007370-A1 | A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |