Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.81 |
| ▸ | PTAFR | P25105 | 1/20 | 0.81 |
| ▸ | HTR1D | P28221 | 1/20 | 0.81 |
| ▸ | HTR2C | P28335 | 1/20 | 0.81 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.81 |
| ▸ | DRD3 | P35462 | 1/20 | 0.81 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.74 |
| ▸ | PRKCG | P05129 | 1/20 | 0.74 |
| ▸ | PRKCB | P05771 | 1/20 | 0.74 |
| ▸ | PRKCA | P17252 | 1/20 | 0.74 |
| ▸ | PRKCH | P24723 | 1/20 | 0.74 |
| ▸ | AKT1 | P31749 | 1/20 | 0.74 |
| ▸ | PRKCI | P41743 | 1/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.74 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.74 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30652294 | 1.00 | ADRA1D (0.81) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL31443474 | 0.92 | RECQL (0.92) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL4661993 | 0.92 | RECQL (0.92) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL2532131 | 0.92 | RECQL (0.84) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL434159 | 0.92 | RECQL (0.84) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL436646 | 0.92 | RECQL (0.84) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL1428475 | 0.92 | RECQL (0.92) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL1394777 | 0.92 | RECQL (0.92) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL7217971 | 0.92 | RECQL (0.92) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL30547610 | 0.92 | RECQL (0.92) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117612741-A | Novel coronavirus infection metabolic profile, and construction method, device, system and application thereof | 首都医科大学附属北京朝阳医院 | 2024-02-27 | — | — | CN | claimed |
| CN-117612741-A | Novel coronavirus infection metabolic profile, and construction method, device, system and application thereof | 首都医科大学附属北京朝阳医院 | 2024-02-27 | — | — | CN | disclosed |
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| US-8394785-B2 | Methods for the treatment and amelioration of urticaria | JADO TECHNOLOGIES GMBH (DE) | 2013-03-12 | — | — | US | disclosed |
| US-20110263531-A1 | METHODS FOR THE TREATMENT AND AMELIORATION OF ATOPIC DERMATITIS | JADO TECHNOLOGIES GMBH | 2011-10-27 | — | — | US | disclosed |
| US-7998945-B2 | Methods for the treatment and amelioration of atopic dermatitis | JADO TECHNOLOGIES GMBH (DE) | 2011-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263531-A1 | METHODS FOR THE TREATMENT AND AMELIORATION OF ATOPIC DERMATITIS | PHOSPHO1, SMPD3, SMPD1 | ADRA1D 875/4885PTAFR 819/4885HTR1D 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.