Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979188 | 0.86 | EPHX2 (0.44) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL29979698 | 0.86 | EPHX2 (0.44) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL28961012 | 0.85 | EPHX2 (0.59) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL28514162 | 0.82 | EPHX2 (0.64) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL5051924 | 0.77 | EPHX2 (1.00) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL3397254 | 0.77 | EPHX2 (1.00) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL2753089 | 0.75 | EPHX2 (0.96) | EPHX2RAB9AKMT2ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL5047929 | 0.73 | EPHX2 (0.93) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL13169536 | 0.73 | EPHX2 (0.83) | EPHX2RAB9AKMT2ANPC1HPGD | |
| SCHEMBL7371442 | 0.73 | EPHX2 (0.64) | EPHX2RAB9AKMT2ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112250633-B | 1,2-di (diphenylphosphine alkyl amido) -1,2-disubstituted ethane and synthesis and application thereof | 浙江大学 | 2022-10-11 | — | — | CN | disclosed |
| WO-2021012949-A1 | 1,2-BIS(DIPHENYLPHOSPHINOALKYLAMIDO)-1,2-DISUBSTITUTED ETHANE AND SYNTHESIS AND USE THEREOF | 浙江大学 | 2021-01-28 | — | — | WO | disclosed |
| CN-112250633-A | 1, 2-di (diphenylphosphine alkyl amido) -1, 2-disubstituted ethane and synthesis and application thereof | 浙江大学 | 2021-01-22 | — | — | CN | disclosed |