Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979188 | 1.00 | EPHX2 (0.44) | EPHX2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL22922973 | 0.86 | EPHX2 (0.62) | EPHX2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL22922972 | 0.84 | EPHX2 (0.43) | EPHX2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL29979370 | 0.84 | EPHX2 (0.43) | EPHX2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL14438183 | 0.71 | SMN1; SMN2 (0.60) | KMT2AHPGDALDH1A1MEN1CYP3A4 | |
| SCHEMBL18677974 | 0.71 | KMT2A (0.75) | KMT2AHPGDALDH1A1MEN1RAB9A | |
| SCHEMBL17346445 | 0.71 | KMT2A (0.75) | KMT2AHPGDALDH1A1MEN1RAB9A | |
| SCHEMBL28961012 | 0.71 | EPHX2 (0.59) | EPHX2KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL11199269 | 0.70 | ALDH1A1 (0.38) | EPHX2ALDH1A1CYP3A4SSTR3 | |
| SCHEMBL19429772 | 0.70 | HTT (0.44) | KMT2AHPGDALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112250633-B | 1,2-di (diphenylphosphine alkyl amido) -1,2-disubstituted ethane and synthesis and application thereof | 浙江大学 | 2022-10-11 | — | — | CN | disclosed |