Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923672 | 0.92 | NAMPT (0.38) | NAMPTMEN1KMT2A | |
| SCHEMBL22923606 | 0.87 | NAMPT (0.41) | NAMPT | |
| SCHEMBL22923683 | 0.87 | NAMPT (0.46) | NAMPT | |
| SCHEMBL22923572 | 0.84 | NAMPT (0.39) | NAMPT | |
| SCHEMBL22923661 | 0.81 | NAMPT (0.50) | NAMPT | |
| SCHEMBL22923645 | 0.80 | NAMPT (0.37) | NAMPT | |
| SCHEMBL22923767 | 0.80 | NAMPT (0.49) | NAMPT | |
| SCHEMBL20159260 | 0.80 | NAMPT (0.51) | NAMPT | |
| SCHEMBL20159601 | 0.80 | NAMPT (0.50) | NAMPT | |
| SCHEMBL20142914 | 0.80 | NAMPT (0.53) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013693-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | WO | disclosed |