Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 18/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923640 | 0.92 | NAMPT (0.42) | NAMPTMEN1KMT2A | |
| SCHEMBL22923682 | 0.89 | NAMPT (0.41) | NAMPT | |
| SCHEMBL22923645 | 0.89 | NAMPT (0.37) | NAMPT | |
| SCHEMBL22923650 | 0.86 | NAMPT (0.35) | NAMPT | |
| SCHEMBL22923525 | 0.82 | NAMPT (0.44) | NAMPT | |
| SCHEMBL22923606 | 0.80 | NAMPT (0.41) | NAMPT | |
| SCHEMBL22923683 | 0.80 | NAMPT (0.46) | NAMPT | |
| SCHEMBL22923734 | 0.79 | NAMPT (0.41) | NAMPT | |
| SCHEMBL22923694 | 0.79 | HDAC2 (0.49) | NAMPT | |
| SCHEMBL20159260 | 0.76 | NAMPT (0.51) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021013693-A1 | ANTIBODY DRUG CONJUGATES (ADCS) WITH NAMPT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | WO | disclosed |