SCHEMBL22923967

SCHEMBL22923967

CCCCN1C(=O)/C(=C/c2cn(Cc3ccccc3)c3ccccc23)C(=O)N1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.57
SIRT5 Q9NXA8 1/20 0.57
MEN1 O00255 9/20 0.53
KMT2A Q03164 9/20 0.53
NR4A1 P22736 1/20 0.50
PDE4A P27815 2/20 0.49
PDE4B Q07343 2/20 0.49
PDE4C Q08493 2/20 0.49
PDE4D Q08499 2/20 0.49
PDE3B Q13370 1/20 0.49
PDE3A Q14432 1/20 0.49
CNR2 P34972 1/20 0.47
POLB P06746 3/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
DHFR P00374 1/20 0.47
MAPT P10636 2/20 0.46
SIRT2 Q8IXJ6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24251280 1.00 SIRT1 (0.57) SIRT1SIRT5MEN1KMT2ANR4A1
SCHEMBL24614121 0.97 SIRT1 (0.60) SIRT1SIRT5MEN1KMT2ANR4A1
SCHEMBL24251263 0.89 KMT2A (0.67) SIRT1SIRT5MEN1KMT2APOLB
SCHEMBL26418060 0.87 KMT2A (0.55) SIRT1SIRT5MEN1KMT2ACNR2
SCHEMBL24614126 0.85 KMT2A (0.60) SIRT1SIRT5MEN1KMT2ANR4A1
SCHEMBL24614128 0.85 KMT2A (0.71) SIRT1SIRT5MEN1KMT2APOLB
SCHEMBL24251264 0.85 KMT2A (0.56) SIRT1SIRT5MEN1KMT2APOLB
SCHEMBL24251250 0.84 KMT2A (0.52) MEN1KMT2APOLBDHFRMAPT
SCHEMBL22923969 0.84 KMT2A (0.52) MEN1KMT2APOLBDHFRMAPT
SCHEMBL24943532 0.83 KMT2A (0.55) SIRT1SIRT5MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162115-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-08-19 WO disclosed
WO-2021014973-A1 WAVELENGTH-SELECTIVE ABSORPTION FILTER AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-01-28 WO disclosed